A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

Renowned statistician David Spiegelhalter shows how we can become better at dealing with what we don't know to make smarter choices in a world so full of puzzling variables. In lucid, lively prose, Spiegelhalter guides us through the principles of probability, illustrating how they can help us think more analytically about everything from medical advice to sports to climate change forecasts.

Daughter. Duhitár-. Dustr. Dukte. Listen to these English, Sanskrit, Armenian and Lithuanian words, all meaning the same thing, and you hear echoes of one of history’s most unlikely journeys. All four languages—along with hundreds of others, from French and Gaelic, to Persian and Polish—trace their origins to an ancient tongue spoken as the last ice age receded. This language, which we call Proto-Indo-European, was born between Europe and Asia and exploded out of its cradle, fragmenting as it spread east and west.

Imagine a world where your brain can be interrogated to learn your political beliefs, your thoughts can be used as evidence of a crime, and your own feelings can be held against you. A world where people who suffer from epilepsy receive alerts moments before a seizure, and the average person can peer into their own mind to eliminate painful memories or cure addictions.

Dr. Topol’s unprecedented, evidenced-based guide is about how you and your family and friends can benefit from new treatments coming available at a faster rate than ever. From his unique position as a leader overseeing millions in research funding, Dr. Topol also explains the fundamental reasons—from semaglutides to AI—that we can be confident these breakthroughs will continue. Ninety-five percent of Americans over sixty have at least one chronic disease and almost as many have two. That is the essential problem this revolution is solving.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

Causal Inference provides a brief and nontechnical introduction to randomized experiments, propensity scores, natural experiments, instrumental variables, sensitivity analysis, and quasi-experimental devices. Ideas are illustrated with examples from medicine, epidemiology, economics and business, the social sciences, and public policy.

There is a robotics revolution underway. A record 3.1 million robots are working in factories right now, doing everything from assembling computers to packing goods and monitoring air quality and performance. A far greater number of smart machines impact our lives in countless other ways—improving the precision of surgeons, cleaning our homes, extending our reach to distant worlds—and we’re on the cusp of even more exciting opportunities.

For listeners of Walter Isaacson’s Steve Jobs and Chris Miller’s Chip War, a riveting look at how Apple helped build China’s dominance in electronics assembly and manufacturing only to find itself trapped in a relationship with an authoritarian state making ever-increasing demands.

We are entering a new technological age in which artificial intelligence and immersive media will transform society at all levels, mediating our lives by altering what we see, hear, and experience. If managed well, this could unleash a new age of abundance. If managed poorly, this technological revolution could easily go astray, compromising our privacy, autonomy, agency, and humanity. Two industry veterans provide a data-driven debate on whether the new world we're creating will be a technological utopia or an AI-powered dystopia and give guidance on how to aim for the best future we can.

In the late 1850s, a physician in New York City used a syringe and glass tube to inject half a drop of sperm into a woman's uterus, marking the first recorded instance of artificial insemination. From that day forward, doctors and scientists have turned to technology in ever more innovative ways to facilitate conception. Fertility Technology surveys this history in all its medical, practical, and ethical complexity, and offers a look at state-of-the-art fertility technology in various social and political contexts around the world.

A New York Times bestselling author and leading expert on market risk argues that seismic shifts in the global economy will trigger a multi-trillion-dollar migration of wealth, tracing the fateful decisions that created this crisis—and outlines new rules of investing for the forward-thinking.

Math has a reputation for being inaccessible. People think that it requires a special gift or that comprehension is a matter of genes. Yet, the greatest mathematicians throughout history, from Rene Descartes to Alexander Grothendieck, have insisted that this is not the case.

Confused about AI and worried about what it means for your future and the future of the world? You’re not alone. AI is everywhere—and few things are surrounded by so much hype, misinformation, and misunderstanding. In AI Snake Oil, computer scientists Arvind Narayanan and Sayash Kapoor cut through the confusion to give you an essential understanding of how AI works, why it often doesn’t, where it might be useful or harmful, and when you should suspect that companies are using AI hype to sell AI snake oil—products that don’t work, and probably never will.

From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic engineering is shaking the core foundations of our lives-sex, war, love, and death. At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

For Blood and Money tells the little-known story of how an upstart biotechnology company created a one-in-a-million cancer drug and how the core team—denied their share of the profits—went and did it again. In this epic saga of money and science, veteran financial journalist Nathan Vardi explains how the invention of two of the biggest cancer drugs in history became (for their backers) two of the greatest Wall Street bets of all time.

Within the next five years, Jeremy Kahn predicts, AI will disrupt almost every industry and enterprise, with vastly increased efficiency and productivity. It will restructure the workforce, making AI copilots a must for every knowledge worker. It will compel us to reimagine how we make art, compose music, and write and publish books. The potential of generative AI to extend our skills, talents, and creativity as humans is undeniably exciting and promising. But while this new technology has a bright future, it also casts a dark and fearful shadow.

While cells are commonly considered the building block of living things, it is actually the communication between cells that brings us to life, controlling our bodies and brains, determining whether we are healthy or sick, and directly influencing how we think, feel, and behave. In The Secret Language of Cells, doctor and neuroscientist Jon Lieff lets us listen in on these conversations, and reveals their significance for everything from mental health to cancer.

In November 2022, a webpage was posted online with a simple text box. It was ChatGPT, and was unlike any app people had used before. It was more human than a customer service agent, more convenient than a Google search. Behind the scenes, battles for control and prestige between the world’s two leading AI firms, OpenAI and DeepMind, who now steers Google's AI efforts, has remained elusive—until now.

Shannon Vallor makes a wide-ranging, prophetic, and philosophical case for what AI could be: a way to reclaim our human potential for moral and intellectual growth, rather than lose ourselves in mirrors of the past. Rejecting prophecies of doom, she encourages us to pursue technology that helps us recover our sense of the possible, and with it the confidence and courage to repair a broken world. Vallor calls us to rethink what AI is and can be, and what we want to be with it.

During the height of the COVID-19 pandemic, one renowned scientist, in his famous bowtie, appeared daily on major news networks such as MSNBC, NPR, the BBC, and others. Dr. Peter J. Hotez often went without sleep, working around the clock to develop a nonprofit COVID-19 vaccine and to keep the public informed. During that time, he was one of the most trusted voices on the pandemic and was even nominated for a Nobel Peace Prize for his selfless work. He also became one of the main targets of anti-science rhetoric that gained traction through conservative news media.

Dreaming is one of the most underappreciated functions of the human brain, yet our very survival as a species depends on it. In This Is Why You Dream, dual-trained neuroscientist and neurosurgeon Dr. Rahul Jandial explores the landscape of our subconscious, tracing the latest cutting-edge dream research and brain science to show why humans have retained the ability to dream across millennia, and how we can now harness its wondrous powers to improve our sleeping and waking lives.

Genomics has transformed the biological sciences. From epidemiology and medicine to evolution and forensics, the ability to determine an organism's complete genetic makeup has changed the way science is done and the questions that can be asked of it. John Archibald explores the science of genomics and its rapidly expanding toolbox. Archibald tells us how the field of genomics is on the cusp of another quantum leap; the implications for science and society are profound.

Bostrom’s previous book, Superintelligence: Paths, Dangers, Strategies (OUP, 2014) sparked a global conversation on AI that continues to this day. That book, which became a surprise New York Times bestseller, focused on what might happen if AI development goes wrong. But what if things go right? Suppose we develop superintelligence safely and ethically, and that we make good use of the almost magical powers this technology would unlock.

What does it mean to be smart? To be human? What do we really want from life and the intelligence we have, or might create? With deep and exclusive reporting, across hundreds of interviews, New York Times Silicon Valley journalist Cade Metz brings you into the rooms where these questions are being answered. Where an extraordinarily powerful new artificial intelligence has been built into our biggest companies, our social discourse, and our daily lives, with few of us even noticing.

Written by an author with plenty of experience holding a scalpel, Dr. David Schneider's in-depth biography is an encompassing history of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing implant revolution of the 20th century.

In June of 2024, thirty-one years after its founding in a Denny’s restaurant, Nvidia became the most valuable corporation on Earth. The Thinking Machine is the astonishing story of how a designer of video game equipment conquered the market for AI hardware, and in the process re-invented the computer. Essential to Nvidia’s meteoric success is its visionary CEO Jensen Huang, who more than a decade ago, on the basis of a few promising scientific results, bet his entire company on AI.

Join journalist Barry Werth as he pulls back the curtain on Vertex, a start-up pharmaceutical company, and witness firsthand the intense drama being played out in the pioneering and hugely profitable field of drug research. Founded by Joshua Boger, a dynamic Harvard- and Merck-trained scientific whiz kid, Vertex is dedicated to designing - atom by atom - both a new life-saving immunosuppressant drug and a drug to combat the virus that causes AIDS.