Haunted by the death of her sister, Finola Shanahan has resolved that she's not worthy of a family of her own and commits to spending her days caring for immigrants in the slums. Unwilling to consider marriage, Finola has perfected the ability to sabotage the relationships her parents arrange for her. At wit's end, her father calls upon the local Irish matchmaker, who pairs her with successful wagonmaker Riley Rafferty.

Emily Leland sheds no tears when her abusive husband is killed in a bar fight, but what awaits her back home in Sweetwater Crossing is far from the welcome and comfort she expected. First she discovers her father has died under mysterious circumstances. Then the house where the handsome new schoolteacher, Craig Ferguson, and his son are supposed to board burns, leaving them homeless. When Emily proposes turning the family home into a boardinghouse, her sister is so incensed that she leaves town.

Katherine Schneider’s life as a dentist in 1913 New York is upended when a patient reveals details of a deadly plot while under the influence of laughing gas. As she is plunged into danger, she seeks help from the dashing Lieutenant Jonathan Birch, a police officer she has long admired from afar.

In 1875 California, Brody MacKenzie arrives at Two Hearts Ranch on a mission to find his runaway brothers, worried they may have fallen into harm. Instead, he finds them thriving at the ranch's school and orphanage under the care of Ellie Hart, a woman with a heart as resilient as the land she calls home.

In 1774, Juliet Catesby lives with her father and sister at Royal Vale, the James River plantation founded by her Virginia family over a century before. Indigo cultivation is her foremost concern, though its export tethers her family to the powerful Buchanan clan of Glasgow, Scotland. When the heir of the Buchanan firm arrives on their shores, Juliet discovers that her father has secretly arranged for one of his daughters to marry the Scot as a means of canceling the family's debt. Confident it will be her younger, lovelier sister, Juliet is appalled when Leith Buchanan selects her instead.