Frances Wynn, the American-born Countess of Harleigh, enjoys more freedom as a widow than she did as a wife. After an obligatory year spent mourning her philandering husband, Reggie, she puts aside her drab black gowns, leaving the countryside and her money-grubbing in-laws behind. With her young daughter in tow, Frances rents a home in Belgravia and prepares to welcome her sister, Lily, arriving from New York - for her first London season.

November 1866: The grisly murder site in London's East End is thronged with onlookers. None of them expect the calmly efficient young woman among them to be a medical doctor, arrived to examine the corpse. Inspector Richard Tennant, overseeing the investigation, at first makes no effort to disguise his skepticism. But Dr. Julia Lewis is accustomed to such condescension . . .

Hugh of Singleton, fourth son of a minor knight, has been educated as a clerk, usually a prelude to taking holy orders. However, feeling no certain calling despite a lively faith, he turns to the profession of surgeon, training in Paris and then hanging out his sign in Oxford. A local lord asks him to track the killer of a young woman whose bones have been found in the castle cesspit. She is identified as the impetuous missing daughter of a local blacksmith, and her young man, whom she had provoked very publicly, is in due course arrested and sentenced at the Oxford assizes.

The Earl of Wrexford possesses a brilliant scientific mind, but boredom and pride lead him to reckless behavior. He does not suffer fools gladly. So when pompous, pious Reverend Josiah Holworthy publicly condemns him for debauchery, Wrexford unsheathes his rapier-sharp wit and strikes back. As their war of words escalates, London's most popular satirical cartoonist, A. J. Quill, skewers them both.

Lady Emily Hardcastle is an eccentric widow with a secret past. Florence Armstrong, her maid and confidante, is an expert in martial arts. The year is 1908 and they've just moved from London to the country, hoping for a quiet life. But it is not long before Lady Hardcastle is forced out of her self-imposed retirement. There's a dead body in the woods, and the police are on the wrong scent. Lady Hardcastle makes some enquiries of her own, and it seems she knows a surprising amount about crime investigation...