
Doctored
Fraud, Arrogance, and Tragedy in the Quest to Cure Alzheimer's
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Narrado por:
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Lyle Blaker
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De:
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Charles Piller
Acerca de esta escucha
“Demonstrates how some of the most accomplished and elite scientific gatekeepers may have lied, cheated, squandered trust and endangered lives.”—The Wall Street Journal
For fans of Empire of Pain and Dopesick, an arresting deep dive into how Alzheimer’s disease treatment has been set back by corrupt researchers, negligent regulators, and the profit motives of Big Pharma.
Nearly seven million Americans live with Alzheimer’s disease, a tragedy that is already projected to grow into a $1 trillion crisis by 2050. While families suffer and promises of pharmaceutical breakthroughs keep coming up short, investigative journalist Charles Piller’s Doctored shows that we’ve quite likely been walking the wrong path to finding a cure all along—led astray by a cabal of self-interested researchers, government accomplices, and corporate greed.
Piller begins with a whistleblower—Vanderbilt professor Matthew Schrag—whose work exposed a massive scandal. Schrag found that a University of Minnesota lab led by a precocious young scientist and a Nobel Prize-rumored director delivered apparently falsified data at the heart of the leading hypothesis about the disease. Piller’s revelations of Schrag’s findings stunned the field and the public.
From there, based on years of investigative reporting, this “seminal account of deceit that will long be remembered” (Katherine Eban, author of Bottle of Lies and Vanity Fair special correspondent) exposes a vast network of deceit and its players, all the way up to the FDA. Piller uncovers evidence that hundreds of important Alzheimer’s research papers are based on false data. In the process, he reveals how even against a flood of money and influence, a determined cadre of scientific renegades have fought back to challenge the field’s institutional powers in service to science and the tens of thousands of patients who have been drawn into trials to test dubious drugs. It is a shocking tale with huge ramifications not only for Alzheimer’s disease, but for scientific research, funding, and oversight at large.
©2025 Charles Piller (P)2025 Simon & Schuster AudioLos oyentes también disfrutaron...
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Historia
Measles, once seemingly defeated, is resurgent around the globe. Why, at a time when biomedical science is so advanced, do parents turn away from vaccination, endangering their own children and the health of the wider population? Using a combination of patient narrative, historical analysis, and scientific research, Dr. Adam Ratner, pediatrician and infectious disease specialist, argues that the reawakening of measles and the subsequent coronavirus pandemic are bellwethers of forgotten knowledge—indicators of decaying trust in science and an underfunded public health infrastructure.
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A must listen
- De Frank Chervenak MD en 04-29-25
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The Corporation in the 21st Century
- Why (Almost) Everything We Are Told About Business Is Wrong
- De: John Kay
- Narrado por: Peter Wicks
- Duración: 14 h y 19 m
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John Kay's incisive overhaul of our ideas about business redefines our understanding of successful commercial activity and the corporation—and describes how we have come to "love the product" as we "hate the producer." This is a brilliant and original work from one of the greatest economists.
De: John Kay
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The Word of Dog
- What Our Canine Companions Can Teach Us About Living a Good Life
- De: Mark Rowlands
- Narrado por: Todd McLaren
- Duración: 7 h y 18 m
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If you have spent any part of your life with a dog, you may have found certain questions popping, unbidden, into your mind: Is my dog living a fulfilled life? Is my dog a good dog? Does my dog love me? Addressing these questions compels you to confront not just your dog's life but yours as well—to think about what fulfillment, and meaning, in life really is. In The Word of Dog, philosopher Mark Rowlands explores these questions and suggests that in dogs we can see hints—faint, shrouded, but discernible—of what a better way of living might look like.
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Tedious and boring
- De Anonymous User en 05-26-25
De: Mark Rowlands
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Doctored
- The Disillusionment of an American Physician
- De: Sandeep Jauhar
- Narrado por: Patrick Lawlor
- Duración: 10 h y 38 m
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Hoping for the stability he needs to start a family, Sandeep Jauhar, an attending cardiologist, accepts a position at a massive teaching hospital on the outskirts of Queens. With a decade's worth of elite medical training behind him, he is eager to settle down and reap the rewards of countless sleepless nights. Instead, he is confronted with sobering truths. Doctors' morale is low and getting lower.
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Frank, inside perspective on the follies of unintended consequences in medical reform
- De JW en 02-25-18
De: Sandeep Jauhar
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Follow the Science
- How Big Pharma Misleads, Obscures, and Prevails
- De: Sharyl Attkisson
- Narrado por: Sharyl Attkisson
- Duración: 12 h y 25 m
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Follow the Science recounts, in exacting detail, how far the pharmaceutical industry and its supporters in medicine, media, and government will go to protect their profits. Attkisson provides shocking examples that reveal the disturbing callousness our government, public health officials, and top researchers are capable of when it comes to the most vulnerable among us. And she explains, in a graphic sense, how some of the most trusted within our society are willing to commit life-threatening ethics violations.
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True Investigative Reporting
- De Robert L. Phillips III en 09-17-24
De: Sharyl Attkisson
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The Age of Choice
- A History of Freedom in Modern Life
- De: Sophia Rosenfeld
- Narrado por: Greg D. Barnett
- Duración: 13 h y 10 m
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The Age of Choice tells the long history of the invention of choice as the defining feature of modern freedom. Taking listeners from the seventeenth century to today, Sophia Rosenfeld describes how the early modern world witnessed the simultaneous rise of shopping as an activity and religious freedom as a matter of being able to pick one's convictions. Similarly, she traces the history of choice in romantic life, politics, and the ideals of human rights. Throughout, she pays particular attention to the lives of women, who have frequently been the drivers of this change.
De: Sophia Rosenfeld
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Ends of the Earth
- Journeys to the Polar Regions in Search of Life, the Cosmos, and Our Future
- De: Neil Shubin
- Narrado por: Fred Berman
- Duración: 7 h y 43 m
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Renowned scientist Neil Shubin has made extraordinary discoveries by leading scientific expeditions to the sweeping ice landscapes of the Arctic and Antarctic. He’s survived polar storms, traveled in temperatures that can freeze flesh in seconds, and worked hundreds of miles from the nearest humans, all to deepen our understanding of our world. Written with infectious enthusiasm and irresistible curiosity, Ends of the Earth blends travel writing, science, and history in a book brimming with surprising and wonderful discoveries.
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Excellent scientific view of the poles
- De Prosanta Chakrabarty en 02-27-25
De: Neil Shubin
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Science Fictions
- How Fraud, Bias, Negligence, and Hype Undermine the Search for Truth
- De: Stuart Ritchie
- Narrado por: Stuart Ritchie
- Duración: 8 h y 35 m
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Science is how we understand the world. Yet failures in peer review and mistakes in statistics have rendered a shocking number of scientific studies useless—or, worse, badly misleading. Such errors have distorted our knowledge in fields as wide-ranging as medicine, physics, nutrition, education, genetics, economics, and the search for extraterrestrial life. As Science Fictions makes clear, the current system of research funding and publication not only fails to safeguard us from blunders but actively encourages bad science—with sometimes deadly consequences.
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Needed Now More Than Ever
- De Todd en 08-06-20
De: Stuart Ritchie
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Meltdown
- Greed, Scandal, and the Collapse of Credit Suisse
- De: Duncan Mavin
- Narrado por: Charles Armstrong
- Duración: 8 h y 3 m
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Credit Suisse was a 166-year-old bastion of global banking. But a veneer of high-class service disguised a darker, much dirtier reality. From its sterile Zurich headquarters, Credit Suisse banked dictators and drug dealers, hid stolen Nazi gold, and helped corrupt bankers fleece the firm's own clients of billions of dollars. Its top executives oversaw a global operation that laundered money for autocrats; they hired spies to track one another through the cobbled streets of the Swiss financial capital; and they helped clients hide their money from the world's tax authorities.
De: Duncan Mavin
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How to Feed the World
- The History and Future of Food
- De: Vaclav Smil
- Narrado por: Joe Jameson
- Duración: 7 h y 30 m
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We have never had to feed as many people as we do today. And yet, we misunderstand the essentials of where our food really comes from, how our dietary requirements shape us, and why this impacts our planet in drastic ways. As a result, in our economic, political, and everyday choices, we take for granted and fail to prioritize the thing that makes all our lives possible: food. In this ambitious, myth-busting book, Smil investigates many of the burning questions facing the world today.
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lots of dense information, hard to absorb.
- De chris en 05-20-25
De: Vaclav Smil
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Three Wild Dogs (and the Truth)
- A Memoir
- De: Markus Zusak
- Narrado por: Markus Zusak
- Duración: 5 h y 28 m
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What happens when the Zusak family opens their home to three big, wild, street-hardened dogs—Reuben, more wolf than hound; Archer, blond, beautiful, destructive; and the rancorously smiling Frosty, who walks like a rolling thunderstorm? The answer can only be chaos: There are street fights, park fights, public shamings, property damages, injuries, hospital visits, wellness checks, pure comedy, shocking tragedy, and carnage that must be heard to be believed.
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Great story, quite the tear jerker
- De Lindsey Shultz en 02-27-25
De: Markus Zusak
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Inevitable
- Inside the Messy, Unstoppable Transition to Electric Vehicles
- De: Mike Colias
- Narrado por: Michael Butler Murray
- Duración: 10 h y 45 m
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The question is no longer if electric vehicles will happen, or even when they'll happen, but how. Veteran automotive reporter Mike Colias takes you inside the transformation in this thoroughly reported profile of the hard pivot in the car business, a $2 trillion industry undergoing the biggest change in its 120-year history—a change that is already sending ripples across the entire global economy.
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Best Book on EVs - Fun and Authoritative
- De LD en 04-16-25
De: Mike Colias
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What the Body Knows
- A Guide to the New Science of Our Immune System
- De: John Trowsdale
- Narrado por: Mike Cooper
- Duración: 11 h y 36 m
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What is our immune system, and how does it work? A vast array of cells, proteins and chemicals spring into action whenever our bodies are damaged, but immunity is not something you can see, touch, or feel. It can fight off malicious bacteria and viruses, locate cancerous growths, and even rewire our brains—but sometimes our own tissues can get caught in its crossfire, with catastrophic consequences. Humans may be the most disease-ridden animals on the planet. Professor John Trowsdale shows how the immune system protects us, and how our bodies invest huge resources to keep it running.
De: John Trowsdale
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The Narrative Brain
- The Stories Our Neurons Tell
- De: Fritz Alwin Breithaupt PhD
- Narrado por: Brian Wiggins
- Duración: 10 h y 4 m
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As humans, we think in stories—stories that allow us to feel and share emotions. In order for this phenomenon to work, our brains and the ways in which we tell stories must be attuned to each other. But how exactly does this happen? Tapping into the essence of thinking in stories, Fritz Breithaupt draws on the latest scientific research, including a retelling study (comparable to the telephone game) with more than 12,000 participants, and experiments in which ChatGPT functions as storyteller.
Misconduct is the antithesis of science
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Extremely thorough work
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A one-sided view of the Alzheimer’s field
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