
Breaking Through
My Life in Science
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Narrado por:
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Eva Magyar
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De:
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Katalin Karikó
Acerca de esta escucha
A powerful memoir from Katalin Karikó, winner of the 2023 Nobel Prize in Physiology or Medicine, whose decades-long research led to the COVID-19 vaccines
“Katalin Karikó’s story is an inspiration.”—Bill Gates
“Riveting . . . a true story of a brilliant biochemist who never gave up or gave in.”—Bonnie Garmus, author of Lessons in Chemistry
A KIRKUS REVIEWS BEST BOOK OF THE YEAR
Katalin Karikó has had an unlikely journey. The daughter of a butcher in postwar communist Hungary, Karikó grew up in an adobe home that lacked running water, and her family grew their own vegetables. She saw the wonders of nature all around her and was determined to become a scientist. That determination eventually brought her to the United States, where she arrived as a postdoctoral fellow in 1985 with $1,200 sewn into her toddler’s teddy bear and a dream to remake medicine.
Karikó worked in obscurity, battled cockroaches in a windowless lab, and faced outright derision and even deportation threats from her bosses and colleagues. She balked as prestigious research institutions increasingly conflated science and money. Despite setbacks, she never wavered in her belief that an ephemeral and underappreciated molecule called messenger RNA could change the world. Karikó believed that someday mRNA would transform ordinary cells into tiny factories capable of producing their own medicines on demand. She sacrificed nearly everything for this dream, but the obstacles she faced only motivated her, and eventually she succeeded.
Karikó’s three-decade-long investigation into mRNA would lead to a staggering achievement: vaccines that protected millions of people from the most dire consequences of COVID-19. These vaccines are just the beginning of mRNA’s potential. Today, the medical community eagerly awaits more mRNA vaccines—for the flu, HIV, and other emerging infectious diseases.
Breaking Through isn’t just the story of an extraordinary woman. It’s an indictment of closed-minded thinking and a testament to one woman’s commitment to laboring intensely in obscurity—knowing she might never be recognized in a culture that is driven by prestige, power, and privilege—because she believed her work would save lives.
©2023 Katalin Karikó (P)2023 Random House AudioLos oyentes también disfrutaron...
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Reseñas de la Crítica
“A riveting testament to resilience and the power of unwavering belief, Breaking Through charts an inspirational journey from growing up in postwar communist Hungary to transforming the world with mRNA.”—Jennifer Doudna, Nobel Prize laureate in chemistry and author of A Crack in Creation
“Katalin Karikó’s story is an inspiration. Anyone who has ever doubted that science, innovation, and persistence can change the world should read this book.”—Bill Gates, #1 New York Times bestselling author of How to Avoid a Climate Disaster
“Karikó’s proven recipe (from the creative Hungarian kitchen) for a breakthrough in science: Start with an insatiable curiosity in education and research. Then, for a few decades, look for gaps in knowledge; work hard for years to fill some of them; don’t give up because of difficulties or circumstances; and, finally, seize the opportunity to help solve one painful problem of humanity, thereby opening new horizons for the future of medicine. Bon appétit, enjoy your sweets!”—Ernő Rubik, inventor of the Rubik’s Cube and author of Cubed
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- De: Lynsey Addario
- Narrado por: Lynsey Addario
- Duración: 9 h
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War photographer Lynsey Addario’s memoir It’s What I Do is the story of how the relentless pursuit of truth, in virtually every major theater of war in the twenty-first century, has shaped her life. What she does, with clarity, beauty, and candor, is to document, often in their most extreme moments, the complex lives of others. It’s her work, but it’s much more than that: it’s her singular calling.
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I think I cried four times
- De Ian en 06-29-24
De: Lynsey Addario
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Run Towards the Danger
- Confrontations with a Body of Memory
- De: Sarah Polley
- Narrado por: Sarah Polley
- Duración: 7 h y 56 m
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In this extraordinary book, Sarah Polley explores what it is to live in one’s body, in a constant state of becoming, learning, and changing. Each of these six essays captures a piece of Polley’s life as she remembers it, while at the same time examining the fallibility of memory, the mutability of reality in the mind, and the possibility of experiencing the past anew, as the person she is now but was not then. As Polley writes, the past and present are in a “reciprocal pressure dance.”
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Really Just a Book About Her Diffcult Moments
- De Andrew en 03-11-22
De: Sarah Polley
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The Deep Places
- A Memoir of Illness and Discovery
- De: Ross Douthat
- Narrado por: Ross Douthat
- Duración: 6 h y 2 m
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In the summer of 2015, Ross Douthat was moving his family, with two young daughters and a pregnant wife, from Washington, DC, to a sprawling farmhouse in a picturesque Connecticut town when he acquired a mysterious and devastating sickness. It left him sleepless, crippled, wracked with pain - a shell of himself. After months of seeing doctors and descending deeper into a physical inferno, he discovered that he had a disease which, according to CDC definitions, does not actually exist.
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Excellent!!
- De D en 11-09-21
De: Ross Douthat
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My Voice
- A Memoir
- De: Angie Martinez, J. Cole - foreword
- Narrado por: Angie Martinez
- Duración: 7 h y 28 m
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In her current reign at Power 105.1 and for nearly two decades at New York's Hot 97, Angie Martinez has had one of the highest rated radio shows in the country. After working her way up as an intern, she burst on the scene as a young female jock whose on-air "Battle of the Beats" segment broke records and became a platform for emerging artists like a young Jay Z. Angie quickly became known for intimate, high-profile interviews, mediating feuds between artists, and taking on the most controversial issues in hip-hop.
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Excellent read, precise imagery, very impressed
- De Tiesha Hogue en 06-05-17
De: Angie Martinez, y otros
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First
- Sandra Day O'Connor
- De: Evan Thomas
- Narrado por: Kirsten Potter
- Duración: 16 h y 33 m
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She was born in 1930 in El Paso and grew up on a cattle ranch in Arizona. At a time when women were expected to be homemakers, she set her sights on Stanford University. When she graduated near the top of her law school class in 1952, no firm would even interview her. But Sandra Day O’Connor’s story is that of a woman who repeatedly shattered glass ceilings - doing so with a blend of grace, wisdom, humor, understatement, and cowgirl toughness.
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Remarkable woman, well served in this book.
- De KathrynVB en 04-05-19
De: Evan Thomas
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An Illuminated Life
- Belle da Costa Greene's Journey from Prejudice to Privilege
- De: Heidi Ardizzone
- Narrado por: Robin Miles
- Duración: 22 h y 8 m
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What would you give up to achieve your dream? When J. P. Morgan hired Belle da Costa Greene in 1905 to organize his rare book and manuscript collection, she had only her personality and a few years of experience to recommend her. Ten years later, she had shaped the famous Pierpont Morgan Library collection and was a proto-celebrity in New York and the art world, renowned for her self-made expertise, her acerbic wit, and her flirtatious relationships. Born to a family of free people of color, Greene changed her name and invented a Portuguese grandmother to enter White society.
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A Remarkable Woman
- De HistoryNerd en 01-25-22
De: Heidi Ardizzone
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The Trip to Echo Spring
- On Writers and Drinking
- De: Olivia Laing
- Narrado por: Kate Reading
- Duración: 10 h y 34 m
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In The Trip to Echo Spring, Olivia Laing examines the link between creativity and alcohol through the work and lives of six of America's finest writers: F. Scott Fitzgerald, Ernest Hemingway, Tennessee Williams, John Berryman, John Cheever, and Raymond Carver. All six of these men were alcoholics, and the subject of drinking surfaces in some of their finest work, from Cat on a Hot Tin Roof to A Moveable Feast.
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Great Narration!!!!!! Great story about 20 Century make writer who suffer with alcoholism. If you like this topic and want more
- De Pamela Abbey en 04-25-21
De: Olivia Laing
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Hunger Makes Me a Modern Girl
- A Memoir
- De: Carrie Brownstein
- Narrado por: Carrie Brownstein
- Duración: 7 h y 4 m
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From the guitarist of the pioneering band Sleater-Kinney, the book Kim Gordon says "everyone has been waiting for" and a New York Times Notable Book of 2015 - a candid, funny, and deeply personal look at making a life - and finding yourself - in music. Before Carrie Brownstein became a music icon, she was a young girl growing up in the Pacific Northwest just as it was becoming the setting for one the most important movements in rock history.
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fussy
- De Ex en 01-09-16
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The Distance Between Us
- A Memoir
- De: Reyna Grande
- Narrado por: Yareli Arizmendi
- Duración: 11 h y 36 m
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In this inspirational and unflinchingly honest memoir, acclaimed author Reyna Grande describes her childhood torn between the United States and Mexico, and shines a light on the experiences, fears, and hopes of those who choose to make the harrowing journey across the border. Reyna Grande vividly brings to life her tumultuous early years in this “compelling...unvarnished, resonant” (BookPage) story of a childhood spent torn between two parents and two countries.
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opened my eyes to the beauty of our stories
- De Evelyn en 09-18-20
De: Reyna Grande
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Under the Big Black Sun
- A Personal History of L.A. Punk
- De: John Doe, Tom Desavia
- Narrado por: Exene Cervenka, Henry Rollins, full cast
- Duración: 7 h y 20 m
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Under the Big Black Sun explores the nascent Los Angeles punk rock movement and its evolution to hardcore punk as it's never been told before. Authors John Doe and Tom DeSavia have woven together an enthralling story of the legendary West Coast scene from 1977 to 1982 by enlisting the voices of people who were there. The book shares chapter-length tales from the authors along with personal essays from famous (and infamous) players in the scene.
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A love song to the early punk days in LA.
- De Brenda en 07-09-16
De: John Doe, y otros
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A Mother's Reckoning
- Living in the Aftermath of Tragedy
- De: Sue Klebold
- Narrado por: Andrew Solomon, Sue Klebold
- Duración: 11 h y 24 m
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On April 20, 1999, Eric Harris and Dylan Klebold walked into Columbine High School in Littleton, Colorado. Over the course of minutes, they would kill 12 students and a teacher and wound 24 others before taking their own lives. For the last 16 years, Sue Klebold, Dylan's mother, has lived with the indescribable grief and shame of that day. How could her child, the promising young man she had loved and raised, be responsible for such horror? And how, as his mother, had she not known something was wrong?
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Sad, but, Ultimately, Self-Serving
- De Gillian en 02-19-16
De: Sue Klebold
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Hope
- A Memoir of Survival in Cleveland
- De: Amanda Berry, Gina DeJesus, Mary Jordan, y otros
- Narrado por: Jorjeana Marie, Marisol Ramirez, Arthur Morey
- Duración: 12 h y 20 m
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Two victims of the infamous Cleveland kidnapper share the story of their abductions, their decade in captivity, and their final, dramatic rescue. On May 6, 2013, Amanda Berry made headlines around the world when she fled a Cleveland area home and called 911, saying: “Help me, I’m Amanda Berry...I’ve been kidnapped, and I’ve been missing for 10 years". A horrifying story rapidly unfolded. Ariel Castro, a local school bus driver, had separately lured Berry, Gina DeJesus, and Michelle Knight to his home, where he kept them chained in the basement.
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A moving read.
- De caroline en 04-28-15
De: Amanda Berry, y otros
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The Ice at the End of the World
- An Epic Journey into Greenland's Buried Past and Our Perilous Future
- De: Jon Gertner
- Narrado por: Fred Sanders, Jon Gertner
- Duración: 12 h y 54 m
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In The Ice at the End of the World, Jon Gertner explains how Greenland has evolved from one of earth’s last frontiers to its largest scientific laboratory. The history of Greenland’s ice begins with the explorers who arrived here at the turn of the 20th century. Their original goal was to conquer Greenland’s seemingly infinite interior. Yet their efforts eventually gave way to scientists who built lonely encampments out on the ice and began drilling - one mile, two miles down.Their aim was to pull up ice cores that could reveal the deepest mysteries of earth’s past.
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Adventure, Science, Advocacy
- De EM Goodkind en 09-08-19
De: Jon Gertner
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A Childhood
- The Biography of a Place
- De: Harry Crews, Tobias Wolff - foreword
- Narrado por: Matt Godfrey
- Duración: 6 h y 43 m
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Harry Crews grew up as the son of a sharecropper in Georgia at a time when “the rest of the country was just beginning to feel the real hurt of the Great Depression but it had been living in Bacon County for years.” Yet what he conveys in this moving, brutal autobiography of his first six years of life is an elegiac sense of community and roots from a rural South that had rarely been represented in this way.
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Story rings true
- De Greg B en 07-26-22
De: Harry Crews, y otros
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Live in Love
- Growing Together Through Life's Changes
- De: Lauren Akins, Mark Dagostino
- Narrado por: Lauren Akins, Thomas Rhett
- Duración: 9 h y 28 m
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Live in Love is a deeply personal memoir that offers inspiring guidance for anyone looking to keep romance alive, balance children and marriage, express true faith, and live a life of purpose.
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AMAZING!!!
- De Kasha Ross en 08-28-20
De: Lauren Akins, y otros
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A Terribly Serious Adventure
- Philosophy and War at Oxford, 1900-1960
- De: Nikhil Krishnan
- Narrado por: Kieran Hodgson
- Duración: 11 h y 48 m
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These were among the questions that philosophers wrestled with in mid-twentieth-century Britain, a period shadowed by war and the rise of fascism. In response to these events, thinkers such as Philippa Foot (originator of the famous trolley problem), Isaiah Berlin, Iris Murdoch, Elizabeth Anscombe, Gilbert Ryle, and J. L. Austin aspired to a new level of watchfulness and self-awareness about language as a way of keeping philosophy true to everyday experience.
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Brilliant in every way!
- De Chuck Stark en 07-05-23
De: Nikhil Krishnan
Lo que los oyentes dicen sobre Breaking Through
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- José
- 01-10-24
Inspiring
Kaitlin's memoirs go beyond her major scientific advances to tell of her search for the unknown and her determination and resilience to find it, even without knowing that doing so would save millions of lives. One of the most inspiring stories I have read, but at the same time it reveals how there is a lot to do to support talent, especially women.
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- Linda Hart
- 11-21-23
Remarkable and inspiring story of grit and perseverance
Remarkable and inspiring story of grit and perseverance. Humanity should be forever grateful. Made me wonder how many researchers, particularly women, who quit before seeing the fruits of their labor because of poor leadership in their labs. The reader's accent created the belief that the book was delivered in the author's voice.
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- Jacob Rios
- 10-29-23
a must listen
this book is a must listen. it’s so inspirational and a lesson for how life should be lived.
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- Amazon Customer
- 11-08-23
Excellent book!
Excellent book! Read it. Wish everyone could read this book. It is a story of grit.
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- Mai Ceesay
- 01-08-24
Phenomenal
Phenomenal and very inspirational. Just wow! Went through several rounds of smiles and cries listening to this book. Thank you for your contribution Dr.!!!
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- Lisa
- 04-06-24
inspiring story
shows how academia works, and how humanity almost missed the contributions of this wonderful scientist.
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- M. Colombo
- 06-02-24
Truly inspiriring
This is an amazing book. Katalin life is truly inspiring. The book it’s well written and well narrated. A Nobel price winner who had to face so many challenges.
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- Stacey
- 08-06-24
Absolutely remarkable!
This is an amazing autobiography by a skilled and determined researcher. She overcame many obstacles to achieve her discoveries and it is fortunate for humanity that she did so, considering how instrumental they were in developing a Covid vaccine. Brava!
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- Josh
- 11-23-24
Love letter to RNA
I enjoyed hearing about this author’s dogged determination in the face of adversity. Her story is inspiring. I admire Katalin Karikó, her voice desperately needs to be heard by the world.
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- Fox2
- 11-27-23
Excellent book
Worthy book to read. Great story that shows the ethics and hard work of Dr. Kariko. Very inspiring and it shows the importance of science in our society. I fully recommend it.
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