After years of trying to become pregnant without success, Rachel Dawson and her husband Thomas felt their dreams had finally come true the day they brought home their newly adopted twin babies. Though the lawyer Baron Bell who arranged for the surrogate mother charged a hefty six-figure fee, one glance into the eyes of their precious children told them it was all worth it - until the birth mother reappeared, first demanding more money, then the twins themselves.

On the surface, these seven women are as different as can be - but each has had her share of bad luck, from cheating husbands to sexist colleagues to a legal system that often doesn't do its job. Now, drawn together by tragedy, they're forging a bond that will help them right the wrongs committed against them and discover an inner strength they didn't know they had. The Sisterhood is learning that when bad things happen, you can roll over and play dead...or you can get up fighting...

Through public triumphs and private sorrows, the men in the Sisters' lives - husbands, friends, colleagues, and lovers - have offered invaluable aid and support. In the process, they've become an informal brotherhood of their own, able to relate to the unique challenges and rewards of life among the vigilantes.

Teresa "Toots" Amelia Loudenberry has crammed a great deal of living - not to mention eight much-loved husbands - into her varied and rewarding life. Newly single, Toots is ready to taste life again, and fate has just handed her the perfect opportunity.

Olivia Lowell always believed her father's claim that her mother died in childbirth, until the shocking day a lawyer informs her that her mother has just passed away, leaving her a fortune. The money comes with a caveat - and a confession. In her will, Olivia's mother reveals that she and two college friends committed a crime long ago, and now she wants Olivia to track down her accomplices and convince them to come clean.

Ellie Bowman barely remembers the incident that put her into a coma. When she awoke, filled with unease, all she knew for certain was that her boyfriend, Rick, was missing. She knew she needed to get away from her old life and recover in safety. With the proceeds of a video game she helped develop, Ellie starts over in rural Missouri, working from her cottage and trusting no one except her friend and business partner.

When Samantha Rainford - newly wed to Douglas Cosmo Rainford III - returns home from her honeymoon to find divorce papers waiting, she's shocked and heartbroken. Then she discovers that she's not the first to be abandoned - she's one of four (or maybe more) ex-Mrs. Rainfords - and decides it's time to put into practice that old truism: Don't get mad, get even.

College senior Lily Madison is on her own and desperate to pay for her last semester of school. With nowhere to turn, she makes the difficult decision to donate her eggs to a fertility clinic. Sam Parker is also a penniless student who supplements his tuition money by visiting a sperm bank. One day, Lily and Sam meet at the clinic and talk about their secret. Despite their obvious attraction, Lily and Sam go their separate ways.

If her abusive husband hadn't tried to kill her and her beloved dog Lucie, Helen Ward might never have left her million-dollar home and run far away. Now Helen's changed her identity and moved across the country, hopeful that she can be safe, happy, maybe even loved. And when she meets college professor Sam Tolliver, she begins to believe fairytales do come true.

A brilliant career and loving friends weren't enough to heal Dr. Sara Killian's aching heart. For brief, magical moment, world famous rock star Dallas Lord was part of her life. Then he was suddenly and tragically taken away. But before he disappeared, Dallas gave Sara a priceless gift - a beautiful love song written just for her. It's a legacy that will take Sara places she'd never dreamed of - into intrigue, betrayal, and deadly danger.

On his thirty-fifth birthday, Jake St. Cloud inherits a fortune - and learns the whereabouts of his mysterious half-brother. On her deathbed, Selma St. Cloud revealed that Jake had a sibling, a product of his father's affair. At last, Jake is in a position to track down Alex Rosario and make amends for their father's past neglect.

In a city built on dreams, Trisha Holiday makes her living moving like one. But out of her dancer's costume, she's as down-to-earth as they come. That's why she ignores the admiring note - and the accompanying $1,000 bill - that arrives backstage after one of her ethereal performances. Yet the sender, a wealthy foreign prince, isn't easily dissuaded. Seven years living and studying in the United States have made Malik long for the freedom to choose his own bride - and the woman he wants is Trisha.

An only child who lost both parents during her first year at college, wealthy heiress Kristine Kelly had made her husband her whole world. But she didn't see what everyone else did: that handsome, charismatic Logan Kelly was a manipulator and a user. Then, one cold December, Kristine got a chilling wake-up call when Logan vanished, along with the eight-million-dollar trust fund she had naively given him the power to control.

Satisfied with her life and a new relationship, Abby Mitchell is most happy to be reunited with her sister, who was separated from her after their parents died. The siblings are planning a sumptuous party, unaware that an uninvited guest is coming, one who'll do anything to help keep the past hidden.

Back in college, Jane Lewis would have given anything to be like homecoming queen Connie Bryan. Instead she was just Plain Jane - overweight, frumpy, and painfully shy. That was then. Today, a lovely and confident Dr. Jane Lewis has a thriving psychotherapy practice, her own radio talk show, a beautiful old Louisiana mansion, and her affectionate, nutty dog, Olive, to keep her company. The only thing missing is someone to share her life.