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Mary B. Addison killed a baby. Allegedly. She didn't say much in that first interview with detectives, and the media filled in the only blanks that mattered: a white baby had died while under the care of a churchgoing black woman and her nine-year-old daughter. The public convicted Mary, and the jury made it official. But did she do it?

New England, 2022. Three years ago, single mother Mallory Dunne received the telephone call every parent dreads—her ten-year-old son, Sam, had been airlifted from summer camp with acute poisoning from a toxic death cap mushroom, leaving him fighting for his life. Now, searching for the donor kidney that will give her son a chance for a normal life, Mallory’s forced to confront two harrowing secrets from her past: her mother’s adoption from an infamous Irish orphanage in 1952, and her own all-consuming summer romance fourteen years earlier with her childhood best friend, Monk Adams.

A woman boards a plane in the African country of Burkina Faso having just completed a targeted assassination for the state of Israel. Two minutes later, her plane is blown out of the sky. Over 6,000 miles away, former Navy SEAL James Reece watches the names and pictures of the victims on cable news. One face triggers a distant memory of a Mossad operative attached to the CIA years earlier in Iraq—a woman with ties to the intelligence services of two nations…a woman Reece thought he would never see again.

The year is 2008 and Samantha Kofer's career at a huge Wall Street law firm is on the fast track - until the recession hits and she gets downsized, furloughed, escorted out of the building. Samantha, though, is one of the "lucky" associates. She's offered an opportunity to work at a legal aid clinic for one year without pay, after which there would be a slim chance that she'd get her old job back. In a matter of days Samantha moves from Manhattan to Brady, Virginia, population 2,200, in the heart of Appalachia, a part of the world she has only read about.

Years after an Easter weekend tragedy devastates a family, they return to the house they grew up in to unearth the many secrets hidden within the nooks and crannies of home.

Ten years ago, Izzy Stone's mother fatally shot her father while he slept. Devastated by her mother's apparent insanity, Izzy, now 17, refuses to visit her in prison. But her new foster parents, employees at the local museum, have enlisted Izzy's help in cataloguing items at a long-shuttered state asylum. There, amid piles of abandoned belongings, Izzy discovers a stack of unopened letters, a decades-old journal, and a window into her own past.

According to Confucius, “an educated woman is a worthless woman,” but Tan Yunxian—born into an elite family, yet haunted by death, separations, and loneliness—is being raised by her grandparents to be of use. Her grandmother is one of only a handful of female doctors in China, and she teaches Yunxian the pillars of Chinese medicine, the Four Examinations—looking, listening, touching, and asking—something a man can never do with a female patient.

"Bloom where you're planted," is the advice Christine Bolz receives from her beloved Oma. But 17-year-old domestic Christine knows there is a whole world waiting beyond her small German village. It's a world she's begun to glimpse through music, books - and through Isaac Bauerman, the cultured son of the wealthy Jewish family she works for.

Yet the future she and Isaac dream of sharing faces greater challenges than their difference in stations. In the fall of 1938, Germany is changing rapidly under Hitler's regime....

Meet Eleanor Oliphant: She struggles with appropriate social skills and tends to say exactly what she's thinking. Nothing is missing in her carefully timetabled life of avoiding social interactions, where weekends are punctuated by frozen pizza, vodka, and phone chats with Mummy. But everything changes when Eleanor meets Raymond, the bumbling and deeply unhygienic IT guy from her office.

Fallon meets Ben, an aspiring novelist, the day before her scheduled cross-country move. Their untimely attraction leads them to spend Fallon's last day in LA together, and her eventful life becomes the creative inspiration Ben has always sought for his novel. Over time and amidst the various relationships and tribulations of their own separate lives, they continue to meet on the same date every year.