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Already well-versed in the natural healing properties of herbs and oils, Jennie Pickett longs to become a doctor. But the Oregon frontier of the 1870s doesn't approve of such innovations as women attending medical school. To leave grief and guilt behind, as well as support herself and her challenging young son, Jennie cares for an elderly woman using skills she's developed on her own. When her patient dies, Jennie discovers that her heart has become entangled with the woman's widowed husband, a man many years her senior.

College student Joe Talbert has the modest goal of completing a writing assignment for an English class. His task is to interview a stranger and write a brief biography of the person. With deadlines looming, Joe heads to a nearby nursing home to find a willing subject. There he meets Carl Iverson, and soon nothing in Joe's life is ever the same. Carl is a dying Vietnam veteran-and a convicted murderer. With only a few months to live, he has been medically paroled to a nursing home after spending thirty years in prison for the crimes of rape and murder.

Alice Wright marries handsome American Bennett Van Cleve hoping to escape her stifling life in England. But small-town Kentucky quickly proves equally claustrophobic, especially living alongside her overbearing father-in-law. So, when a call goes out for a team of women to deliver books as part of Eleanor Roosevelt’s new traveling library, Alice signs on enthusiastically. The leader, and soon Alice's greatest ally, is Margery, a smart-talking, self-sufficient woman who's never asked a man's permission for anything.

Meet Ove. He’s a curmudgeon—the kind of man who points at people he dislikes as if they were burglars caught outside his bedroom window. He has staunch principles, strict routines, and a short fuse. But behind the cranky exterior there is a story and a sadness. So when one November morning a chatty young couple with two chatty young daughters move in next door and accidentally flatten Ove’s mailbox, it is the lead-in to a comical and heartwarming tale of unkempt cats, unexpected friendship, and the ancient art of backing up a U-Haul.