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Saffron's two sisters, Cadmium and Rose, and her brother Indigo were all named from a color chart by their mother Eve, a fine-arts painter. When Saffron, known as Saffy, discovers that her name is not on the chart, it soon leads to another discovery. She has been adopted.

On a cold spring night in 1952, a huge meteorite fell to earth and obliterated much of the East Coast of the US, including Washington, DC. The ensuing climate cataclysm will soon render the Earth inhospitable for humanity, as the last such meteorite did for the dinosaurs. This looming threat calls for a radically accelerated effort to colonize space and requires a much-larger share of humanity to take part in the process. Elma York’s drive to become the first lady astronaut is so strong that even the most dearly held conventions of society may not stand a chance against her.