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Ben Barres was known for his groundbreaking scientific work and for his groundbreaking advocacy for gender equality in science. In this book, completed shortly before his death, Barres (born Barbara Barres in 1954) describes a life full of remarkable accomplishments. Barres recounts his early life and felt even as a very young child that he was assigned the wrong gender. After years of being acutely uncomfortable in his own skin, Barres transitioned from female to male. It was after transitioning that he realized how differently male and female scientists are treated.

Sy Montgomery's popular 2011 Orion magazine piece, "Deep Intellect", about her friendship with a sensitive, sweet-natured octopus named Athena and the grief she felt at her death, went viral, indicating the widespread fascination with these mysterious, almost alien-like creatures. Since then Sy has practiced true immersion journalism, from New England aquarium tanks to the reefs of French Polynesia and the Gulf of Mexico, pursuing these wild, solitary shape-shifters.

As a botanist and professor of plant ecology, Robin Wall Kimmerer has spent a career learning how to ask questions of nature using the tools of science. As a Potawatomi woman, she learned from elders, family, and history that the Potawatomi, as well as a majority of other cultures indigenous to this land, consider plants and animals to be our oldest teachers.