Wayne Thompson

The bestselling author of Leonardo da Vinci and Steve Jobs returns with a “compelling” (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.

Known in health care circles for his ability to fix ailing hospitals, Dr. David Shulkin was originally brought into government by President Obama, in an attempt to save the broken Department of Veterans Affairs. When President Trump made him VA secretary, Dr. Shulkin was as shocked as anyone. Yet this surprise was trivial compared to what Shulkin encountered as the VA secretary: a team of political appointees devoted to stopping anyone - including the secretary himself - who stood in the way of privatizing the organization and implementing their agenda.

Early studies of the human brain used a simple method: Wait for misfortune to strike - strokes, seizures, infectious diseases, horrendous accidents - and see how victims coped. In many cases their survival was miraculous, if puzzling. Observers were amazed by the transformations that took place when different parts of the brain were destroyed, altering victims' personalities. With the lucid, masterful explanations and razor-sharp wit his fans have come to expect, Kean explores the brain's secret passageways.

The burgeoning new science of epigenetics offers a cornucopia of insights - some comforting, some frightening. For example, the male fetus may be especially vulnerable to certain common chemicals in our environment, in ways that damage not only his own sperm but also the sperm of his sons. And it’s epigenetics that causes identical twins to vary widely in their susceptibility to dementia and cancer. But here’s the good news: unlike mutations, epigenetic effects are reversible. Indeed, epigenetic engineering is the future of medicine.

Origins explains the soul-stirring leaps in our understanding of the cosmos. From the first image of a galaxy birth to Spirit rover's exploration of Mars, to the discovery of water on one of Jupiter's moons, coauthors Neil deGrasse Tyson and Donald Goldsmith conduct a galvanizing tour of the cosmos with clarity and exuberance.

The extraordinary Siddhartha Mukherjee has written a biography of the gene as deft, brilliant, and illuminating as his extraordinarily successful biography of cancer. Weaving science, social history, and personal narrative to tell us the story of one of the most important conceptual breakthroughs of modern times, Mukherjee animates the quest to understand human heredity and its surprising influence on our lives, personalities, identities, fates, and choices.

Listeners will find here not only the country’s leading conservative thinker offering a pas­sionate defense of limited government, but also a highly independent mind whose views - on feminism, evolution and the death penalty, for example - defy ideological convention. Things That Matter also features several of Krautham­mer’s major path-breaking essays - on bioeth­ics, on Jewish destiny and on America’s role as the world’s superpower - that have pro­foundly influenced the nation’s thoughts and policies.