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Chemist Elizabeth Zott is not your average woman. In fact, Elizabeth Zott would be the first to point out that there is no such thing as an average woman. But it’s the early 1960s and her all-male team at Hastings Research Institute takes a very unscientific view of equality. Except for one: Calvin Evans; the lonely, brilliant, Nobel–prize nominated grudge-holder who falls in love with—of all things—her mind. True chemistry results.

When the long-cherished statue of the Santo Nino de Atocha disappears, village leaders decide to keep the news from the Church hierarchy for fear of reprisal. They suspect the culprits are among local hippies, Protestants, drug dealers, Anglos and other outsiders. But when the statue mysteriously reappears and their beloved chapel sacristan is attacked, favorite son Jay Sierra and his pal, Ernie Lucero, team up to investigate.