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Amy Nicols (Lizzy Caplan) was an FBI agent with a dogged need to protect everyone—until that instinct caused her to mishandle a crisis, lose innocent lives, and lose her job. Now a civilian working in private security, that mistake still haunts her. One morning on the commuter train, she overhears a young couple plotting a murder. Ignoring warnings from her family and friends, Amy’s instinct to protect and serve compels her to investigate. But the further she goes, the more she finds her own life in danger.

Some doors are locked for a reason.... While 11-year-old Nora Davis was up in her bedroom doing homework, she had no idea her father was killing women in the basement. Until the day the police arrived at their front door. Decades later, Nora's father is spending his life behind bars, and Nora is a successful surgeon with a quiet, solitary existence. Nobody knows her father was a notorious serial killer. And she intends to keep it that way. Then Nora discovers one of her young female patients has been murdered.

For Melanie Drake, school guidance counselor in a small Virginia town, the day’s challenges typically involve a playground scuffle or a student skipping school. It’s worlds away from her previous career as a vital part of the Office of Special Investigations. There, she devoted herself heart and soul to covert operations, the riskier the better.

Quinn Alexander has committed an unthinkable crime. To avoid spending her life in prison, Quinn makes a run for it. She leaves behind her home, her job, and her family. She grabs her passport and heads for the northern border before the police can discover what she's done. But when an unexpected snowstorm forces her off the road, Quinn must take refuge at the broken-down, isolated Baxter Motel. The handsome and kindly owner, Nick Baxter, is only too happy to offer her a cheap room for the night. Unfortunately, the Baxter Motel isn't the quiet safe haven it seemed to be.

Sleep deprived and overwhelmed, first-time mom Jenn is struggling to adapt to her new role. Frustrated with her loving but preoccupied husband and still grieving the death of her own mother, she feels isolated and depressed. It’s only when she joins a new-moms’ group that she starts to think she’s finally getting back on track. Until Isabel, the group’s leader, suddenly disappears.

Owen falls ill with food poisoning, leaving Julie to attend a neighborhood holiday party alone. When she wakes up, half-naked in her neighbor's bathtub, Julie doesn't know how to tell Owen, the police, her friends—anyone—that she has been sexually assaulted. So she keeps it secret until she realizes that she's pregnant with her assailant's baby.

Some places seem too beautiful to be touched by horror. Summit Lake, nestled in North Carolina’s Blue Ridge Mountains, is that kind of place. But two weeks ago, Becca Eckersley, a first-year law student and daughter of a powerful attorney, was brutally murdered there. Now the town is reeling with grief, and the police are baffled.

Eve has a good life. She wakes up each day, kisses her husband Nate, and heads off to teach math at the local high school. All is as it should be. Except… Last year, Caseham High was rocked by a scandal involving a student-teacher affair, with one student, Addie, at its center. But Eve knows there is far more to these ugly rumors than meets the eye. Addie can’t be trusted. She lies. She hurts people. She destroys lives. At least, that’s what everyone says. But nobody knows the real Addie. Nobody knows the secrets that could destroy her. And Addie will do anything to keep it quiet…

Sisters. Soul mates. Strangers. Molly Raven lives a quiet, structured life in London, finding comfort in security and routine. Her identical twin, Katie, living in New York, is the exact opposite: outgoing, spontaneous, and adventurous. But when Molly hears that Katie has died, possibly murdered, she is thrown into unfamiliar territory. As terrifying as it is, she knows she must travel across the ocean and find out what happened. But as she tracks her twin’s final movements, cracks begin to emerge.

It's a blindingly hot summer. International visitors surge into Sydney's Darling Harbour. Two-year-old Tommy is sailing his toy boat in the park there with his mother Phoebe. Tommy vanishes into thin air. The following winter, taunting notes written as nursery rhymes begin arriving at his parents' home. Little Boy Blue, where did you go? Who led you away? Only I know.